As Laboratory Scientist, temporary 3 years, in Formulation and Process Development, you are part of the Department “Pharmaceutical Development” in Pharma Technical Development Biologics Europe in Basel, Switzerland. The department Pharmaceutical Development is responsible for the development of parenteral drug products from Phase 0 up to Launch. Activities encompass formulation and manufacturing process development for parenteral drug products for all clinical stages and the market, the transfer of product and process to commercial manufacturing sites, commercial product support and line extension development. Within Pharmaceutical Development, you will join the Cell and Gene Therapy team, who is working on the pharmaceutical development of viral vector gene therapy products.
Your major responsibilities in this position are the following:
In team with qualified laboratory personnel, you are providing laboratory support to the pharmaceutical development operations of viral vector gene therapy formulations: Planning and execution of formulation screening, stability studies, as well as process development studies of AAV, lentivirus and other related gene therapy parenteral formulations
Evaluation and implementation of new methods and technologies, presentation of data in relevant forums, scientific contributions (e.g. publications and conference talks), co-supervision of research projects and initiation of new research activities in the laboratories
Contribution to a culture of innovation, scientific strength and technical rigor within the area of Gene therapy
Contribution to the organizational development of Pharmaceutical Development PTD Biologics Europe.
Your Qualification:
As the successful candidate you hold a Bachelor or a Master Degree in pharmaceutical sciences, chemistry, chemical/process engineering, biochemistry, biotechnology, or related fields. You have preferably knowledge and some experience in the following areas:
Gene therapy formulation and product development, ideally with viral vectors
Relevant technologies and processes e.g. parenteral formulation development, aseptic manufacturing, biochemical and biophysical analytical techniques (e.g. DLS, SEC-MALS, ddPCR), lyophilization
Good communication skills and collaborative behaviors, with end-to-end and global thinking, independent organizational and planning abilities
Knowledge or experience in digital tools, ELN, data analytics is a plus
Good command of English. German knowledge is a plus.
Good IT knowledge. Ability to use data analysis and visualization software systems such as Excel, GraphPad Prism, JMP, R Studio, Fiji.
If you can contribute with your talents and strengths to this role, you are welcome to apply. Please be aware a few candidates have already been identified internally following a targeted approach. If you have questions please check our FAQs and videos on careers.roche.ch/faq
Roche is an equal opportunity employer.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
